Center for Oxygen Microscopy and Imaging
The Centre for Oxygen Microscopy and Imaging (COMI) was established in 2005 with funding from the Danish National Research Foundation.
Drawing on the strengths of an interdisciplinary team, one goal of COMI is to develop the tools and methods needed to create dynamic oxygen-based images, including singlet oxygen based images, of heterogeneous samples that range from glassy polymers to biological cells.
On one level, these images provide fundamental information about specific oxygen-dependent phenomena such as the photoinitiated death of cells. On another level, these studies allow us to address a plethora of other significant issues which include mechanisms of diffusion-dependent intracellular signalling, parameters that influence nonlinear optical transitions, ab initio computations on large solvated molecules, mass transport in solvent-swollen gels, and the effects of metal nanoparticles in optical experiments.
News
Lars Dalgaard has joined the Center for Oxygen Microscopy and Imaging, COMI, as a visiting professor. His principal focus is to study the photochemistry of selected sulfur-containing molecules and proteins, including their response to reactive oxygen species. Among other things, this work is pertinent for studying cell signaling events and the modes of action for many drugs and drug metabolites.
Lars Dalgaard has a background as organic chemist (Aarhus University PhD, 1974). For many years, he was head of the Department of Drug Metabolism at Lundbeck A/S, but is now an independent consultant and adjunct professor at the University of Copenhagen (pharmacy).
