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Christian Jørgensen receives Marie Skłodowska-Curie Fellowship

The Marie Skłodowska-Curie Individual Fellowship seeks to help the best and most promising researchers by helping them set up their research in new countries among other things. This is the case with Christian Jørgensen, who will move from the US to Denmark and start a position as postdoc at the Department of Chemistry, Aarhus University in January 2022.

2021.07.20 | Jakob Laust Hviid

Portrait of Christian Jørgensen

Christian Jørgensen

 

Christian Jørgensen has received the grant for the project “Computational Modelling of the Human Brain Lipidome”. The project is focused on developing a computational model of the brain’s blood-brain barrier with a focus on a special pumping mechanism. This pumping mechanism will play a crucial in distributing medicine in the human brain.

Christian Jørgensen’s project is twofold. The first challenge is focused on dosage of medicine in the brain. Only about 2% of the medicine distributed to the brain actually enters the brain. This is primarily due to the blood-brain barrier, which partly functions as a defence mechanism, keeping unknown substances out of the brain. The second challenge is specifically focused on the P-glycoprotein – a membrane protein that, under the use of energy, pumps a large amount of substances out of living cells in the brain. That means that certain substances, like chemotherapeutic drugs, that enters the brain have difficulty keeping the clinical level it needs to have an effect.

Basically, Christian Jørgensen will research in how to manipulate with the human brain’s defence mechanisms, so patients can be medicated more effectively in the future. The grant itself is set to €207,312 over a two-year period. More funding might be applied for after the two years.

Chris Jørgensen is 32 years old but already has an impressive academical background. He got his undergraduate and graduate degrees at Oxford University and then spent two years at Université de Lorraine as a research assistant. Hereafter, he went back to England where he got his PhD at King’s College in London. Following that, he occupied two postdoc positions at Johns Hopkins and Georgetown University, respectively. From January 2022, as mentioned, he will be part of our department – specifically he will join Professor Birgit Schiøtt and her research group to continue his research in the human brain and its chemistry.

We look forward to welcoming Christian to the department.

Public / media, Grant, Health and disease, Department of Chemistry