Department of Chemistry

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How small can you make nucleic acid nanostructures and why does it matter?

Researchers from the interdisciplinary Nanoscience Center (iNANO) and Department of Chemistry at Aarhus University have significantly advanced the field of nucleic nanostructures, potentially transforming their application in biomedicine.

Researchers from iNANO have used the artificial acyclic (L)- threoninol nucleic acid (aTNA) to form nanostructures such as a 3D cube and a pyramid with dimensions below 5 nm. The structures are stable in serum and have potential as drug delivery vehicles. J. Am. Chem. Soc. 2024, 146, 29, 20141-20146
Revised 29.06.2026
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Fie Noer Christensen