Department of Chemistry

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 Department of Chemistry Research Research areas and groups Organic chemistry Bioorganic Chemistry Publications

Publications

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Rasmussen, T. S., Koldsø, H., Nakagawa, S., Kato, A., Schiøtt, B. & Jensen, H. H. (2011). Synthesis of uronic-Noeurostegine –a potent bacterial β-glucuronidase inhibitor. Organic & Biomolecular Chemistry, 9, 7807-7813. https://doi.org/10.1039/C1OB06038D
Sinning, S., Musgaard, M., Jensen, M., Severinsen, K., Celik, L., Koldsoe, H., Meyer, T., Bols, M., Jensen, H. H., Schiøtt, H. B. & Wiborg, O. (2010). Binding and Orientation of Tricyclic Antidepressants within the Central Substrate Site of the Human Serotonin Transporter. Journal of Biological Chemistry, 285(11), 8363-8374. https://doi.org/10.1074/jbc.M109.045401
Krag, J., Christiansen, M. S., Petersen, J. & Jensen, H. H. (2010). Direct chemical glycosylation with pentenyl- and thioglycoside donors of N-acetylglucosamine. Carbohydrate Research, 345, 872-879.
Slamova, K., Marhol, P., Bezouska, K., Lindkvist, L., Hansen, S. G., Kren, V. & Jensen, H. H. (2010). Synthesis and biological activity of glycosyl-1H-1,2,3-triazoles. Bioorganic & Medicinal Chemistry Letters, 20, 4263-4265.
Rasmussen, T. S. & Jensen, H. H. (2010). Synthesis and glycosidase inhibitory activity of noeurostegine†—a new andpotent inhibitor of ß-glucoside hydrolases. Organic & Biomolecular Chemistry, 8, 433-441.
Koldsø, H., Severinsen, K., Tran, T. T., Celik, L., Jensen, H. H., Wiborg, O., Schiøtt, B. & Sinning, S. (2010). The two enantiomers of citalopram bind to the human serotonin transporter in reversed orientations. Journal of the American Chemical Society, 132(4), 1311-22. https://doi.org/10.1021/ja906923j
Koldsø, H., Severinsen, K., Tran, TT., Celik, L., Jensen, H. H., Wiborg, O., Schiøtt, B. & Sinning, S. (2010). The two enantiomers of citalopram bind to the human serotonin transporterin reverse orientations. Journal of American Chemical Society, 132(4), 1311-22.
Nielsen, S., Pedersen, C. M., Hansen, S. G., Petersen, M. D., Sinning, S., Wiborg, O., Jensen, H. H. & Bols, M. (2009). An extended study of dimeric phenyl tropanes. Bioorganic & Medicinal Chemistry, 17(14), 4900-9. https://doi.org/10.1016/j.bmc.2009.06.007
Schjøth-Eskesen, C. & Jensen, H. H. (2009). Efficient Arndt-Eistert Synthesis of Selective 5-HT7 Receptor Antagonist SB-269970. Synthetic Communications, 3243-3253. https://doi.org/10.1080/00397910902737155
Hansen, S. G. & Jensen, H. H. (2009). Microwave Irradiation as an Effective Means of Synthesizing Unsubstituted N-Linked 1,2,3-Triazoles from Vinyl Acetate and Azides. SYNLETT: Accounts and Rapid Communications in Chemical Synthesis, 2009(20), 3275-3278.
Allman, S. A., Jensen, H. H., Vijayakrishnan, B., Garnet, J. A., Leon, E., Liu, Y., Anthony, D. C., Sibson, N. R., Feizi, T., Matthews, S. & Davis, B. G. (2009). Potent Fluoro-oligosaccharide Probes of Adhesion in Toxoplasmosis. ChemBioChem, 10, 2522-2529.
Christensen, H., Christiansen, M. S., Petersen, J. & Jensen, H. H. (2008). Direct formation of ß-glycosides of N-acetyl glycosamines mediated by rare earth metal triflates. Organic & Biomolecular Chemistry, 6, 3276-3283.
I. van Kasteren, S., O. Kramer, H., Jensen, H. H., J. Campbell, S., Kirkpatrick, J., Oldham, N., C. Anthony, D. & G. Davis, B. (2007). Expanding the diversity of chemical protein modifications allows post-translational mimicry. Nature, 446, 1105-1109. http://www.nature.com/nature/journal/v446/n7139/pdf/nature05757.pdf
Jensen, H. H., Pedersen, C. M. & Mikael, B. (2007). Going to extremes: "Super" armed glycosyl donors in glycosylation chemistry. Chemistry: A European Journal, 13(27), 7576-7582.
Boye, S. V., Ortega-Caballero, F., Sinning, S., Wiborg, O., Jensen, H. H. & Bols, M. (2007). High dopamine transporter selectivity can be displayed by remarkably simple non-nitrogen containing inhibitors. Bioorganic & Medicinal Chemistry Letters, 17(21), 6019-6025.
Bols, M. & Jensen, H. H. (2006). Stereoelectronic Substituent Effects. Acc. Chem. Res., 39, 259-265.
Johnston, B., Jensen, H. H. & Pinto, B. M. (2006). Synthesis of Sulfonium Analogues of Disaccharides and their conversion to chain-extended homologues of Salacinol: New glycosidase inhibitors. J. Org. Chem., (71), 259-265.
Gregersen, A., Pedersen, C. M., Jensen, H. H. & Bols, M. (2005). On the electronic effects from OH groups. Synthesis and investigation of tetrahydroxylated azabicycloheptanes. Organic & Biomolecular Chemistry, 3, 1514-1519.
Jensen, H. H., Nordstrøm, L. U. & Bols, M. (2004). The disarming effect of the 4,6-acetal group on glycoside reactivity. Torsional or electronic ? Journal of the American Chemical Society, 126(30), 9205-9213.
Jensen, H. H. & Bols, M. (2003). Steric Effects are not the Cause of the Rate Difference in Hydrolysis of Stereoisomeric Glycosides. Org. Lett., 5, 3419-3421.
Bols, M., Liang, X. & Jensen, H. H. (2002). Equatorial Contra Axial Polar Substituents. The Relation of a Chemical Reaction to Stereochemical Substituent Constants. Journal of Organic Chemistry, 67, 8970-8974.
Lillelund, V., Jensen, H. H., Liang, X. & Bols, M. (2002). Recent Developments of Transition State Analogue Glycosidase Inhibitors of Non-Natural Product Origin. Chemical Reviews, 102, 515-553.
Jensen, H. H., Lyngbye, L., Jensen, A. & Bols, M. (2002). Stereoelectronic Substituent Effects in Polyhydroxylated Piperidines and Hexahydropyridazines. Chemistry: A European Journal, 8, 1218-1226.
Jensen, H. H., Jensen, A., Hazell, R. & Bols, M. (2002). Synthesis and investigation of L-fuco- and D-glucurono-azafagomine. Journal of the Chemical Society, Perkin Transactions 1, 1190-1198.
Jensen, H. H., Lyngbye, L. & Bols, M. (2001). A Free Energy Relationship between the Rate of Acidic Hydrolysis of Glycosides and the pKa of Isofagomines. Angewandte Chemie International Edition, 40, 3447-3449.

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Revised 17.04.2023
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Henrik Helligsø Jensen