Advanced Functional Materials – Alexander Zelikin's group
Artificial Internalizing Receptor Affords Fast, Potent, Specific Drug Delivery to the Chemically Engineered Cells
Researchers from Alexander Zelikin’s group at Aarhus University perform chemical engineering of mammalian cells
Specifically, they designed new artificial internalizing receptors and were able to achieve specific, targeted drug delivery to the one cell with the artificial receptors within a mixed cell population.
The mode of drug delivery was found to be significantly more potent and much faster compared to the use of the pristine drug.
Furthermore, the bio-orthogonality of these new receptors provides a new and dedicated route of communication to chemically engineered cells.
Additional information | |
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External funding | Dependent Research Fund Denmark, Novo Nordisk Foundation |
| Conflict(s) of interest | None |
Link to scientific article | Artificial Internalizing Receptor Affords Fast, Potent, Specific Drug Delivery to the Chemically Engineered Cells: |
Contact | Alexander Zelikin Department of Chemistry, Aarhus University E-mail: zelikin@chem.au.dk |